Analytical Scientist

Description:

The Analytical Scientist role in Analytical Sciences/Quality Control Laboratories will be responsible for provision of analytical methods, data and information using advanced analytical mass spectrometry techniques in supporting individual site and network projects.  This information may be structural or forensic in nature.  It will involve analysis at ultra-trace levels.  The development and validation of the methods and their associated lifecycle will be a key aspect of the role.  The assets involved may be small molecules, peptides, therapeutic proteins, sRNAs, gene therapy and drug conjugates. These assets maybe pipeline or commercial.  The lifecycle management of existing technologies will be a further aspect of the role.  Given the increasing need for more in-depth molecule information and the increasing complexity of assets the identification of and implementation of new or improved technologies will be required.  As all the information generated will be used to support manufacturing objectives the active participation in cross functional teams will be required to understand manufacturing and regulatory requirements while also providing the analytical perspective to ensure overall success.



Key Responsibilities:



Analytical Sciences Support
 

• Support the introduction, validation and on-going technical agenda for pipeline and commercial assets
• Develop and validate robust scientifically advanced methods with the required performance attributes to satisfy stakeholder needs
• Execute testing protocols in accordance with local procedure and regulatory requirements
• Develop strong links with Global Regulatory Affairs and participate in the preparation and review of regulatory submissions
• As required provide training or mentorship to other QC or cross functional team members
• Act as SME for mass spectrometry technologies and / or business systems within QC. This may include the identification, sourcing, installation, and qualification of new equipment
  
   

Leadership/ Site Management
 

• Proactively support management decisions and strategy
• Be a role model for Analytical Sciences/Quality Control team members in terms of performance and behaviours
• Influence the Business/ external partners on critical issues to meet end goals – understand the external context/environment to achieve these goals
• Attend and contribute to relevant technical fora
  
   

Pre-Requisites
 

• Candidates must be mobile to US based organizations after a defined qualification period at the recruiting site.
  
   

Job Specific Pre-requisites


 

• Deep technical expertise in separation sciences, spectroscopy, hyphenated mass spectrometry techniques (MS and MSn.) and their application particularly in the field of proteomics
• With safety as the priority excellent laboratory techniques
• Proficiency in the use of multiple instrument platforms (Thermo, Agilent, Waters etc.) and associated software platforms (Chromeleon, Excalibur)
• Strong technical problem-solving ability both independently and as part of a team
• Motivated to work independently to produce high quality work product in an efficient manner
• High attention to detail in all aspects of the work
  
   

Educational/Experience Requirements
 

• Minimum PhD in Science
• Preferred 3-5 years of recent bench experience in a laboratory environment, relating to mass spectrometry